The exact cause of an enlarged spleen in ferrets is at this time unknown. There seems to be links
between splenomegaly and serious illness' (ie: lymphosarcoma, insulinoma) An enlarged spleen is
common in ferrets, especialy in ferrets over 3 years of age. An enlarged spleen can cause extreme
lethargy, and in some cases a high fever. In many cases removal of the spleen is nescessary .
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